Jake thought Nicole was the perfect girl. Nicole thought Jake was just another clown, cut from the same cloth as his best friend, Mike. After Nicole harshly rejects Jake in his attempt at a date, Jake vows he would never treat a guy like that if he were a girl. The next day, his unintentional wish comes true as they wake up in each others' rooms...and bodies. Jake and Nicole quickly learn that being the opposite sex has its challenges. Not knowing how this happened or if and when they will change back, they soon realize they will need to work together or risk wrecking each others' lives. Along the way, they may just find they have more in common than they thought possible.