The 2012 presidential elections represented the second consecutive defeat for the Republican Party, and its fourth defeat out of the last six presidential elections. In recent years both Republican and Democratic strategists and pundits have spoken of an emerging Democratic Party "lock" on the Electoral College and speculated that even in the wake of Republican victories in Congress, presidential candidates are still at a major disadvantage due to the party's increasing demographic and geographic isolation.

In Altered States, Thomas Holbrook looks at change in party fortunes in presidential elections since 1972, documenting the magnitude, direction, and consequences of changes in party support in the states. He finds that the Democrats do not have a "lock" on the Electoral College, but that their position has improved dramatically over the past forty years in a number of formerly competitive or Republican-leaning states in the Northeast, Southeast, and Southwest. Republican candidates have made many fewer gains, mostly improving their position in "misplaced," formerly Democratic states, such as Kentucky and West Virginia, or in already deeply Republican states in the Plains and Mountain West. Holbrook looks at the ways that changes in the racial and ethnic composition of the state electorates, internal (state to state) and external (foreign born) migratory patterns, and changes in other key demographic and political characteristics drive these changes. Additionally, he explores the ways
in which increasing partisan polarization at the national level has altered group-based party linkages and contributed to changes in party support at the state level. These factors, along with an increasingly inefficient distribution of Republican votes, have converted what was once a Republican edge in electoral votes to an advantage for Democratic presidential candidates.