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Assessing Ocular Toxicology in Laboratory Animals

Assessing Ocular Toxicology in Laboratory Animals

by Margaret Collins and Andrea B Weir
Hardback
Publication Date: 03/12/2012

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Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes.

The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.
ISBN:
9781627031639
9781627031639
Category:
Pharmacology
Format:
Hardback
Publication Date:
03-12-2012
Language:
English
Publisher:
Humana Press Inc.
Country of origin:
United States
Pages:
322
Dimensions (mm):
235x155x23mm
Weight:
6.88kg

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