the early life of an animal or human. This is a book about the collaboration between Hubel and Wiesel, which began in 1958, lasted until about 1982, and led to a Nobel Prize in 1981. It opens with
short autobiographies of both men, describes the state of the field when they started, and tells about the beginnings of their collaboration. It emphasizes the importance of various mentors in their lives, especially Stephen W. Kuffler, who opened up the field by studying the cat retina in 1950, and founded the department of neurobiology at Harvard Medical School, where most of their work was done. The main part of the book consists of Hubel and Wiesel's most important publications. Each
reprinted paper is preceded by a foreword that tells how they went about the research, what the difficulties and the pleasures were, and whether they felt a paper was important and why. Each is also
followed by an afterword describing how the paper was received and what developments have occurred since its publication. The reader learns things that are often absent from typical scientific publications, including whether the work was difficult, fun, personally rewarding, exhilarating, or just plain tedious. The book ends with a summing-up of the authors' view of the present state of the field. This is much more than a collection of reprinted papers. Above all it tells the story of an
unusual scientific collaboration that was hugely enjoyable and served to transform an entire branch of neurobiology. It will appeal to neuroscientists, vision scientists, biologists, psychologists,
physicists, historians of science, and to their students and trainees, at all levels from high school on, as well as anyone else who is interested in the scientific process.
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