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Current Topics in Microbiology and Immunology

Current Topics in Microbiology and Immunology

Ergebnisse der Mikrobiologie und Immunitaetsforschung

by H. KoprowskiW. Arber P. H. Hofschneider and others
Paperback
Publication Date: 01/03/2012

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Ever since arbovirus infections became known and their relative importance assessed, experiments were designed to elucidate the mode of transmission and the most important natural hosts responsible for perpetuating the infection in nature. Human infections and the disease in wild rodents, birds, and domestic animals were studied in relation to viremia and distribution of the infectious agent in the organism. With increasing epidemiological studies it became apparent that the neural manifestations of the disease are very uncommon, confined only to a small percentage of individuals of the most susceptible species. Various factors have been proposed to explain why in certain instances the virus becomes establish ed in the central nervous system and causes a serious or lethal disease. For example, differences in the virulence of the virus strains, varying susceptibility of individuals of one species, or intercurrent circumstances facilitating access of the virus to the central nervous system were alleged. Also, various possible routes of entry of the virus into the brain and spinal cord have been considered.
ISBN:
9783642461200
9783642461200
Category:
Immunology
Format:
Paperback
Publication Date:
01-03-2012
Language:
English
Publisher:
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Country of origin:
Germany
Pages:
234
Dimensions (mm):
244x170x12mm
Weight:
0.42kg

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