Clinically relevant study end points in rectal cancer.- Neoadjuvant treatment in rectal cancer: Do we always need radiotherapy?- Treatment dilemmas in patients with synchronous colorectal liver metastases.- Pancreatic surgery: beyond the traditional limits.- Adjuvant therapy for pancreatic cancer.- Radiotherapy of the pancreas: state of the art in 2012.- Adenocarcinoma of the GEJ: gastric or oesophageal cancer?- Why is there a change in patterns of GE cancer?- Open or minimally invasive resection for oesophageal cancer?- Criteria for selecting the best multimodal therapy.- When is the definitive radiochemotherapy the treatment of choice?- Radiotherapy of gastroesophageal junction (GEJ) cancer.- Optimizing neoadjuvant chemotherapy through the use of early response evaluation by PET .- Optimal surgery for gastric cancer: is more always better?- Can adjuvant chemoradiotherapy replace extended lymph node dissection in gastric cancer?- Predicting the response to chemotherapy in gastric adenocarcinoma: who benefits from neoadjuvant chemotherapy?- Prediction of response and prognosis by a score including only pretherapeutic parameters in 410 neoadjuvant treated gastric cancer patients.- Selecting the best treatment for an individual patient.