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Genetic Disorders of Human Sexual Development

Genetic Disorders of Human Sexual Development

by Robert P. EricksonLeonard Pinsky and R. Neil Schimke
Hardback
Publication Date: 29/07/1999

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There have been many exciting advances in our understanding of mammalian sex determination and differentiation in the last decade. Using these advances to elucidate clinical conditions of abnormal sexual development, the authors bring together great expertise in molecular endocrinology, molecular genetics, and dysmorphology. The text begins with a discussion of normal gonadal and sexual development that presents enough embryology, biochemistry, and endocrinology to
make the remaining chapters easy to assimilate. Then the authors discuss overarching clinical issues that are common to genetic abnormalities of gonadal and sexual development, providing a detailed
account of genetic causes of gonadal maldevelopment, followed by a compendium of the singular, syndromal, endocrinologic, and systemic-metabolic genetic causes of sexual maldevelopment. The final section describes genetic forms of gamete failure. Seldom dogmatic, this unconventional textbook frequently presents alternatives, highlights speculation, raises questions, and attempts to provide answers. Yet it will be a uniquely valuable reference on an area of genetic medicine where
much has happened in recent years. This book will be welcomed by medical geneticists, genetic counselors, endocrinologists, gynecologists, urologists, and students who need fully-referenced information
about the genetic aspects of humans sexual maldevelopment in order to better manage their patients and their patients families.
ISBN:
9780195109078
9780195109078
Category:
Medical genetics
Format:
Hardback
Publication Date:
29-07-1999
Language:
English
Publisher:
Oxford University Press Inc
Country of origin:
United States
Pages:
432
Dimensions (mm):
263x185x31mm
Weight:
0.95kg

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