Part I General issues.- Characteristic and specificity of trace analysis.- Quality evaluation of analytical results - errors classification, uncertainty estimation.- Calibration problems in trace analysis.- Certified reference materials in trace analysis.- Wet decomposition methods in inorganic trace elemental analysis.- Extraction methods in trace analysis.- Part II Application.- Trace analysis of selected organic compounds.- Analysis of drugs impurities.- Elemental analysis of food products.- Trace analysis for Metabolomics and metabonomics.- Determination of selected drugs and their metabolites in biological fluids.- Forensics I: Analytical methods in examination of forensic traces.- Forensics II: Micro traces in clinical and forensic toxicology.- Part III Special aspects.- Inorganic and bioinorganic speciation analysis - selected problems.- Quantification of platinum metals in biological and environmental samples.- Determination of volatile organic compounds by hyphenated chromatographic techniques.- Analysis of radionuclides.