From artificial neural net / game theory / semantic applications, to modeling tools, smart manufacturing systems, and data science research - this book offers a broad overview of modern intelligent methods and applications of machine learning, evolutionary computation, Industry 4.0 technologies, and autonomous agents leading to the Internet of Things and potentially a new technological revolution. Though chiefly intended for IT professionals, it will also help a broad range of users of future emerging technologies adapt to the new smart / intelligent wave. In separate chapters, the book highlights fourteen successful examples of recent advances in the rapidly evolving area of intelligent systems. Covering major European projects paving the way to a serious smart / intelligent collaboration, the chapters explore e.g. cyber-security issues, 3D digitization, aerial robots, and SMEs that have introduced cyber-physical production systems. Taken together, they offer unique insights into contemporary artificial intelligence and its potential for innovation.