Jessica's art-viewing Italian vacation is interrupted by a pair of gunmen who steal a painting and kill a retired police officer in the process. Agreeing to help identify the crooks should they be caught, Jessica returns to Cabot Cove and puts the shocking experience behind her.

Months later, Wayne Simsbury, the stepson of an old friend, comes to her for help. Wayne's father has been shot to death. Not only has Wayne's stepmother, Marlise, been charged with the murder, but Wayne himself claims to have witnessed the crime. Unsure what to do, he has sought out Jessica--the one person his stepmother had always claimed could help with any problem.

Now, on top of a seemingly open-and-shut murder case to crack in Chicago, Jessica finds herself back in Italy helping the police make their case against the art thieves--and she faces a looming danger that may connect the Italian killers to the fate of her old friend....