This book summarizes the research findings presented at the 2nd International Conference on Novel & Intelligent Digital Systems (NiDS 2022). NiDS 2022 was implemented virtually due to COVID-19 restrictions, on September 29-30, 2022, under the auspices of the Institute of Intelligent Systems. NiDS lays special emphasis on the novelties of intelligent systems and on the interdisciplinary research which enables, supports, and enhances artificial intelligence (AI) in software development. It promotes high-quality research, creating a forum for the exploration of challenges and new advances in AI, and addresses experts, researchers, and scholars in the fields of artificial and computational intelligence in systems and in computer sciences in general, enabling them to learn more about pertinent, strongly related, and mutually complementary fields. The conference promotes an exchange of ideas, reinforcing and expanding the network of researchers, academics, and market representatives.