Approximately 4.1 million people live in the three states of the Yucatan Peninsula: Quintana Roo, Yucatan, and Campeche. Some 30 municipalities are in a coastal territory of almost 2,000 linear kilometers, spanning the oil fields of the Gulf of Mexico to the world-renowned beaches of Cancan, just north of the second-largest barrier reef in the world. The peninsula's natural assets also include notable Mayan temples. With poverty far from eliminated, and economic development opportunities beckoning in agriculture, manufacturing, and hydrocarbon development, the region faces growing risks from environmental hazards. Oil spills, hurricanes, coral bleaching, extreme flooding, and erosion have all been experienced over the past decade. Based on preliminary identification of environmental priorities, this report explores selected topics that aim to inform decision-making in the region. A general context of integrated coastal zone management is used to explore issues, constraints, and potential solutions. The role of geomorphology is examined with a view to identifying how shore management plans can contribute to improved coastal management. Economic studies find that the main environmental health risks in the peninsula result in more than 1,000 premature deaths every year and in more than 9.36 million days lost to illnesses. These risks generate substantial economic losses, representing 2.2-3.3 percent of gross regional income. Scenarios relating to the economic cost of extreme weather events generate similar levels of damages: 1.4-1.5 percent of GDP in 2020 and 1.6-2.3 percent of GDP in 2050. A social accounting matrix examines the social and environmental interconnectedness to the various parts of the economy. An institutional analysis considers the mandates of existing institutions in the states, and of the potential role that regulatory measures may contribute to environmentally sustainable development without undermining economic growth prospects. The report concludes with options for consideration in the years ahead.