Part1 Problem Diagnosis: A general overview of the origins and nature of chemical exposure problems.- Introduction.- anatomical and physiological perspectives on human exposure to chemicals.- archetypical chemical exposure problems.- Part2 a public health risk assessment taxonomy: nomenclatural components, concepts, principles,& evaluation strategies.- principles and concepts in risk assessment.- attributes of a public health risk assessment.- general basic planning considerations for a chemical exposure characterization activity.- Part 3 the risk assessment framework & paradigm for chemical exposure problems.- principal elements of a the public health risk assessment process for chemical exposure problems.- chemical hazard determination.- exposure assessment: analysis of human intake of chemicals.- determination of chemical toxicity.- chemical risk characterization.- uncertainty and variability issues in public health risk evaluation.- Part4 development of public health risk management strategies for human exposure to chemicals.- determination of 'acceptable' and 'safe' levels for human exposure to chemicals.- design of public health risk management programs.- utility of risk assessment in public health policy decisions.- Part5 Appendices