This volume explores innovative visions for 21st century learning. It describes the experiences of teachers implementing new technology, presents research studies that highlight effective strategies and technologies, and shares lessons learned from a unique researcher-practitioner mentoring model. This book examines in detail the causal relationship between the COVID-19 pandemic the radical rethinking of education and opportunities provided by new technologies for effective teaching and learning that has followed. Educational approaches that worked well, challenges that were difficult to overcome, and potential benefits of effective technology integration encourage readers to reimagine education for themselves and implement practices that can strengthen the future of online K-12 education, going forward.