This book contains the contributions presented at the 8th International KES Conference on Smart Education and e-Learning (KES SEEL 2021), which being held as a virtual conference on June 14-16, 2021. It contains high-quality peer-reviewed papers that are grouped into several interconnected parts: smart education; smart e-learning; smart education: systems and technology; smart education: case studies and research; digital education and economics in smart university, smart university development: organizational, managerial and social Issues; smart universities and their Impact on students with disabilities. This book serves as a useful source of research data and valuable information on current research projects, best practices, and case studies for faculty, scholars, Ph.D. students, administrators, and practitioners- all those who are interested in smart education and smart e-learning.