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Spinal Muscular Atrophy

Spinal Muscular Atrophy

Disease Mechanisms and Therapy

by Sergey PaushkinCharlotte J. Sumner and Chien-Ping Ko
Hardback
Publication Date: 28/11/2016

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Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development.

This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development.

This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases.

ISBN:
9780128036853
9780128036853
Category:
Neurosciences
Format:
Hardback
Publication Date:
28-11-2016
Language:
English
Publisher:
Elsevier Science & Technology Books
Country of origin:
United States
Dimensions (mm):
276.23x215.9mm

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