Ostensibly a guidebook to melancholia or depression, Burton's masterpiece is really an all-encompassing examination of the human condition.

The Anatomy of Melancholy is the vast and only work by Robert Burton, the seventeenth-century English priest and scholar. It 'opens and cuts up' the condition of melancholy, or depression, as we know it today, and in doing so explores a dizzying range of additional topics including goblins, beauty, the geography of America, digestion, the passions, alcohol and kissing.

Burton believed that reading was a cure for melancholy, and so the book itself - one of the most unique and uncategorizable works of all time - can be seen as a tonic for the very condition it describes.