This book is a collection of twenty original essays on the history of science and mathematics, written in honor of D.T. Whiteside. The topics covered embrace the main themes of Whiteside's scholarly work, emphasizing Newtonian topics including: mathematics and astronomy, Newton's manuscripts, Newton's Principia, Newton and eighteenth-century mathematics and physics, and optics and dynamics after Newton. The focus of these themes gives the volume considerable coherence, and these essays make available important original work on Newton and the history of the exact sciences.