"A new concept of Microchimerism and its Important Role in Autoimmune diseases, Cancer, Wound healing, etc."

Microchimerism is the presence of cells from one individual in another genetically distinct individual.

Pregnancy is the main cause of natural microchimerism through transplacental bi-directional cell trafficking between mother and fetus.

In addition to a variety of cell-free substances, it is now well-recognized that some cells are also exchanged in pregnancy.

Furthermore, it is now known that microchimerism persists decades later both in mother and in her progeny.

The consequences of pregnancy-related microchimerism are under active investigation.

However, many researchers have suggested a close relationship linking fetal microchimerism and the development of autoimmune diseases.

Fetal microchimerism is emerging as a potential contributing factor in certain diseases, including cancer.

Parallel studies in animal and human pregnancy suggest that microchimeric fetal cells play a role in wound healing.

An effort has been made in this Booklet to discuss the role of Fetal Microchimerism - a potential contributing factor in wound healing, certain diseases, including cancer etc. along with several relevant illustrations.

…Dr. H. K. Saboowala.

M.B.(Bom) .M.R.S.H.(London)