Like the first edition, this is a seminal textbook for the advanced practice nursing care of the seriously ill and dying. This comprehensive work addresses all aspects of palliative care including physical, psychological, social, and spiritual needs. It brings to the forefront current issues of health equity, managing through crisis, and meeting the needs of diverse populations. Each chapter contains case examples and a strong evidence base to support the highest quality of care. The text is written by leaders in the field and includes authors who have pioneered the role of the advanced practice nurse in palliative care. This volume offers advanced practice content and practical resources for clinical practice across all settings of care and encompassing all ages, from pediatrics to geriatrics. This newly revised edition has been reorganized to meet the needs of the APRN according to role delineation and practice issues. It offers foundation information on leadership, practice, and the various roles of the APRN as an administrator, educator, policy advocate, and researcher. The various settings of APRN work includes acute care settings (clinical care unit, intensive care unit, and emergency department), clinic (specialty care, primary care, and palliative care), community, rehabilitation, residential facilities, and telehealth. This edition also gives particular attention to special populations, including chapters on health disparities, economic disadvantages for urban dwellers, members of the LGBTQ+ community, Veterans, and Survivorship. There are sections wholly devoted to pediatric care, end of life communication, and the ethics APRNs have to navigate on a daily basis. Written by current APRNs for fellow APRNs, this text provides practical resources for clinical practice across a variety of topics.