This innovative and wide-ranging volume is the first systematic exploration of the multifaceted relationship between human bodies and machines in classical antiquity. It examines the conception of the body and bodily processes in mechanical terms in ancient medical writings, and looks into how artificial bodies and automata were equally configured in human terms; it also investigates how this knowledge applied to the treatment of the disabled and the diseased in the ancient world. The volume examines the pre-history of what develops, at a later stage, and more specifically during the early modern period, into the full science of iatromechanics in the context of which the human body was treated as a machine and medical treatments were devised accordingly. The volume facilitates future dialogue between scholars working on different areas, from classics, history and archaeology to history of science, philosophy and technology.