This book constitutes the refereed proceedings of the 2021 International Conference on Business Intelligence and Information Technology (BIIT 2021) held in Harbin, China, during December 18–20, 2021. BIIT 2021 is organized by the School of Computer and Information Engineering, Harbin University of Commerce, and supported by Scientific Research Group in Egypt (SRGE), Egypt. The papers cover current research in electronic commerce technology and application, business intelligence and decision making, digital economy, accounting informatization, intelligent information processing, image processing and multimedia technology, signal detection and processing, communication engineering and technology, information security, automatic control technique, data mining, software development, and design, blockchain technology, big data technology, artificial intelligence technology.