This issue of Sleep Medicine Clinics, edited by Dr. Jason C. Ong in collaboration with Consulting Editor, Teofilo Lee-Chiong, is devoted to Cognitive-Behavioral Therapies for Insomnia. Topics covered in this issue include: CBT-I in Children and Adolescents; Delivering CBT-I in Patients with Medical and Psychiatric Comorbidities; CBT-I and Women’s Health: Sex as a Biological Variable; Delivering CBT-I in Military Personnel; Using Mindfulness Meditation in the Treatment of Insomnia; Brief Behavior Therapy for Insomnia (BBTI); Intensive Sleep Retraining; CBT-I and Hypnotic Medications: Considerations and Controversies; CBT-I and Acute Insomnia: Considerations and Controversies; Measuring Outcomes for CBT-I in the Real World; Delivering CBT-I in a Health Care System; Determining an Appropriate Candidate for CBT-I; and Online Delivery of CBT-I: Considerations and Controversies.