The Federal Medical Investigators, a division of CDC, continue their search for answers of unsolved medical deaths in the United States. The FMI agents are invited to Virginia Beach upon the request of Future Innovations Today for DNA evaluations for the purpose of discovering the gene responsible for their ESP abilities. They are also put through a battery of various brain scans. Pending F.I.T.'s test results, Agent Simon Woods, Agent Janet Bennett and the FMI agents are sent to Pine Bluff, Arkansas to unravel the unexplained deaths of five people over the past several days. The victims became deaf, then mute, then blind before taking their last breath. The FMI agents may face the Grim Reaper due to the evil intentions of The Circle toward the agents.