This book constitutes the refereed post-conference proceedings of the 24th International Conference on Enterprise Information Systems, ICEIS 2022, This conference was held virtually due to the COVID-19 crisis, during April 25-27, 2022.

The 20 full papers included in this book were carefully reviewed and selected from 197 submissions. They were organized in topical sections as follows: Databases and Information Systems Integration; Artificial Intelligence and Decision Support Systems; Information Systems Analysis and Specification; Human-Computer Interaction; and Enterprise Architecture.