A comprehensive overview of the molecular and cellular mechanisms that link chronic inflammation to cancer. It examines how chronic inflammation promotes tumor development by driving genetic mutations, epigenetic changes, and the disruption of critical cellular pathways. Key signaling networks are explored in detail, revealing their central roles in cancer progression, immune suppression, and therapy resistance.

Chronic inflammation is a silent yet powerful driver of cancer, altering genetic and epigenetic landscapes to promote tumor progression, immune evasion, and therapy resistance. This comprehensive volume unpacks the intricate molecular mechanisms linking inflammation and oncogenesis, from oxidative DNA damage to epigenetic modifications that rewire cellular fate.

Examining key pathways such as NF-kB, STAT3, and TGF-ß, this text provides a rigorous yet accessible analysis of inflammation-driven tumorigenesis. With a focus on genetic mutations, histone modifications, and therapeutic targets, it bridges fundamental research with clinical implications, offering insights into novel intervention strategies. This text discusses how reactive oxygen species, DNA damage, and epigenetic reprogramming work together to create a permissive environment for malignancy. Insights into the involvement of immune modulation and the microbiome further underscore the complexity of inflammation-driven cancers.