This comprehensive handbook presents fundamental aspects, fabrication techniques, introductory materials on microbiology and chemistry, measurement techniques, and applications of microfluidics and nanofluidics. The first volume of the handbook focuses on physics and transport phenomena along with life sciences and related applications. It provides newcomers with the fundamental science background required for the study of microfluidics and nanofluidics. In addition, the advanced techniques and concepts described in the text will benefit experienced researchers and professionals.