This publication provides a model academic curriculum covering the entire spectrum of nuclear security topics for a master’s degree programme or for an academic certificate programme in nuclear security. The first edition, entitled Educational Programmes in Nuclear Security, was published in 2010. Since then, the body of knowledge in the field of nuclear security has grown substantially and the IAEA Nuclear Security Series has expanded to cover more topics. The current publication takes into account the latest IAEA guidance, as well as feedback from the International Nuclear Security Education Network (INSEN) community and other international experts. The publication can be used by university curriculum developers as well as faculty and instructors from institutions that are implementing or considering educational programmes in nuclear security.