Once the haunt of Jack the Ripper, London's East End is a vibrant mix of history and new ideas, but the trendy galleries of Brick Lane disguise a seedy underside where unthinkable crimes bring terror to the innocent.

Artist and young mother Sandra Gilles disappears without trace after leaving her three-year-old daughter, Charlotte, with a friend at the Columbia Road Flower Market. Her lawyer husband, Naz Malik, is devastated - but he's also the prime suspect in a murder investigation.