Dear colleagues.

I published this eBook with my talented and enthusiastic coauthor, PharmD Dua'a Nayef Suleiman Alqhaiwi, after days of research and evidence gathering. The seminal work "Pharmacotherapeutics of Erectile Dysfunction" explores the complex world of ED pharmacology. With ED prevalence rising worldwide, understanding pharmacotherapeutic options is more important than ever. This extensive review covers the pharmacodynamics, pharmacokinetics, clinical efficacy, safety profiles, and therapeutic considerations of ED medications. To find all evidences, we search Medline, Embase, CENTRAL, Web of Science, Scopus, and Google Scholar. Articles from 2023 to April 2024 are searched. We aim to balance search precision and sensitivity to gather the latest and most relevant evidence-based knowledge. We have comprehensive erectile dysfunction and pharmacotherapy materials for medical, surgical, clinical pharmacy, pharmacological consultants, specialists, mentors, residents, and students. The book begins with an overview of ED pathophysiology and then discusses common pharmacological agents, including PDE5 inhibitors, prostaglandin E1 analogues, testosterone replacement therapy, and emerging therapies like stem cell and gene therapy. Dissecting each class of medications reveals their mechanisms of action, dosing regimens, side effects, and contraindications. The book also discusses how combination therapies and new treatment methods improve ED outcomes. Comorbidities like diabetes, cardiovascular disease, and neurogenic disorders, as well as specific populations like the elderly, are addressed with special care. This eBook is invaluable for healthcare professionals, researchers, and students studying ED management. This book helps readers navigate the complex world of ED pharmacotherapy and improve patient care and quality of life by synthesising the latest evidence-based research and clinical expertise. The eBook has 11 chapters with multiple sections. Each chapter has Guiding Key Points, MCQ with Answers, and References. The "MCQs with Guiding Answer" section in each of the 11 chapters averages 14 multiple-choice questions (ranging from 5 to 30). Importantly, each multiple-choice question (MCQ) has a chapter-extracted guiding answer. This eBook contains 147 MCQs and Guidance Answers.