The year is 1348, and the most devastating pandemic in history, The Black Death, known as The Great Mortality, is ravaging the world. The youngest son of a nobleman, 17-year-old Thomas de Parr is to become a monk at Tintern Abbey in Wales. But when he travels to England and meets a young woman who steals his heart, he questions his calling to the Church. As the deadly plague advances, his family's honor is threatened by a vengeful tale with life-changing consequences for Thomas, and he must now fight for his own destiny.

In this first episode of the three-part Plagues and Princes series, Thomas faces an unseen enemy personified as the epitome of evil. Festering in the background are the machinations of an ambitious rogue who will stop at nothing to achieve a life of riches and comfort. Will Thomas endure and come to believe in himself?