This book includes original, peer-reviewed research articles from International Conference on Advances in Computer Engineering and Communication Systems (ICACECS 2021), held in VNR Vignana Jyoythi Institute of Engineering and Technology (VNR VJIET), Hyderabad, Telangana, India, during 13–14 August 2021. The book focuses on “Smart Innovations in Mezzanine Technologies, Data Analytics, Networks and Communication Systems” enlargements and reviews on the advanced topics in artificial intelligence, machine learning, data mining and big data computing, knowledge engineering, semantic Web, cloud computing, Internet on Things, cybersecurity, communication systems, and distributed computing and smart systems.