This book gathers a selection of peer-reviewed papers presented at the 4th Big Data Analytics for Cyber-Physical System in Smart City (BDCPS 2022) conference held in Bangkok, Thailand, on December 16–17. The contributions, prepared by an international team of scientists and engineers, cover the latest advances and challenges made in the field of big data analytics methods and approaches for the data-driven co-design of communication, computing, and control for smart cities. Given its scope, it offers a valuable resource for all researchers and professionals interested in big data, smart cities, and cyber-physical systems.