This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
Epub (Kobo), Epub (Adobe)
Publication Date: 23/06/2021
- ISBN:
- 9783030648534
- 9783030648534
- Category:
- Organic chemistry
- Format:
- Epub (Kobo), Epub (Adobe)
- Publication Date:
- 23-06-2021
- Language:
- English
- Publisher:
- Springer International Publishing
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