In consultation with Consulting Editor, Dr. Jan Foster, Drs. Garbee and Danna have put together a state-of the-art issue of the Critical Care Nursing Clinics devoted to Quality Outcomes and Costs. Clinical review articles are specifically devoted to the following: Information Technology, Electronic Medical Records, and Practice Alerts; Telehealth Use to Promote Quality Outcomes and Reduce Costs; Impact of a Mobility Team on ICU Patient Outcomes; MACRA and MIPS Impact on Quality and Cost Outcomes; Leadership’s Impact on Quality, Outcomes, and Costs; Big Data Sets Use for Quality, Outcomes, and Cost; Pediatric Quality Metrics Related to Quality Outcomes and Cost; Geriatric Outcomes Related to Quality and Cost; Mental Health/Behavioral Health Metrics; Obstetric Quality Outcomes and Cost; Emergency Department Throughput; and Veteran Outcomes. Readers will come away with the latest information they need to improve quality and improve out comes in critically ill patients.