The Book Research Methodology: From Problem Statement to Research Questions explains the crucial role of research problems and research questions in the scientific research process. Research problems must be clearly stated and connected to the necessary resources and capabilities required for their resolution. Research questions, derived from the problem statement, guide the research process and can inspire adjustments to the problem statement. Constructing a research problem statement is a challenging task that requires a mix of subject matter knowledge, imagination, and intuition to identify gaps in the research. Researchers should explore multiple researchable puzzles and scenarios during this stage, allowing flexibility and potential redirection in their research endeavors. Research questions guide the investigation and help researchers stay on track, ensuring the research provides meaningful answers and contributes to the existing knowledge in the field. A good research question aids in planning, analyzing, and evaluating the research project effectively. The presence of multiple research questions should not compromise the primary question, which forms the basis of the study plan, hypothesis, and subsequent statistical analyses.