The Ontology of Physics for Biology

The Ontology of Physics for Biology

by Daniel L. CookJohn H. Gennari and Maxwell L. Neal
Epub (Kobo), Epub (Adobe)
Publication Date: 14/12/2023

Share This eBook:

  $83.99

This book introduces semantic representations of multiscale, multidomain physiological systems that link to qualitative reasoning and to quantitative analysis of biophysical processes in health and disease. Two major public health problems, diabetes and hypertension, serve as use-cases to illustrate the depth and rigor of such representations for logical inference and quantitative analysis. Central to this approach is the Ontology of Physics for Biology (OPB) that formally represents the foundations of classical physics and engineering system dynamics that are the basis for our understanding of biomedical entities, processes, and functional relationships.


Furthermore, we introduce OPB-based software for annotating and abstracting available biosimulation models for reuse, recombination, and for archiving of physics-based biomedical knowledge. We have formalized and leveraged physics-based biological knowledge as a working view of physiology and biophysics from three distinct perspectives: (1) biologists and biomedical investigators, (2) biophysicists and bioengineers, and (3) biomedical ontologists and informaticists. We present a logical and intuitive semantics of classical physics as a tool for mediating and translating biophysical knowledge among biomedical domains.


Daniel L. Cook, MD, PhD


John H. Gennari, PhD


Maxwell L. Neal, PhD

ISBN:
9780429892325
9780429892325
Category:
Biology
Format:
Epub (Kobo), Epub (Adobe)
Publication Date:
14-12-2023
Language:
English
Publisher:
CRC Press

This item is delivered digitally

Reviews

Be the first to review The Ontology of Physics for Biology.