This book describes Vasculitis Diseases, Diagnosis and Treatment and Related Diseases
Vasculitis is an inflammatory condition of the blood vessels
Inflammation may involve pain, redness, warmth in the affected tissues.
If a blood vessel is inflamed, it can cause narrowing
Poor blood flow may cause cells of organs to stop living
Vasculitis can affect the arteries, veins and capillaries
Large blood vessel inflammation include Takayasu's Arteritis
The moderate blood vessels include Kawasaki and Polyarteritis
The small blood vessel includes Henoch Schonlein purpura and polyangiitis
Diagnosis is by the microscopic examination of the blood vessel biopsy
Angiography of the inflamed blood vessels is also diagnostic.
Treatment of vasculitis includes corticosteroids and cytotoxic medicines.
The goal is to stop the immune response that caused the inflammation.
-An original poem by Kenneth Kee
Vasculitis is a disorder that involves inflammation in the blood vessels.
Inflamed Blood Vessels (Vasculitis) happens if the immune system attacks the blood vessels by mistake.
This attack may happen as the result of an infection, a medicine, or another disease or disorder.
“Inflammation” indicates the body’s response to injury, such as injury to the blood vessels.
Inflammation may involve the pain, redness, warmth, swelling and the loss of function in the involved tissues.
In vasculitis, inflammation can lead to serious problems.
Complications are dependent on which blood vessels, organs, or other body systems are involved.
Vasculitis can have an effect on any of the body's blood vessels.
These are arteries, veins, and capillaries.
Arteries bring the blood from the heart to the body's organs.
Veins bring the blood from the organs and limbs back to the heart.
Capillaries join the small arteries and veins.
If a blood vessel is inflamed, it can become narrow or close off.
This restricts or prevents blood flow through the vessel.
The interruption in blood flow produced by inflammation can injure the body's organs.
Signs and symptoms are dependent on which organs have been injured and the extent of the injury.
The normal symptoms of inflammation such as fever, general aches and pains are frequent among people who have vasculitis.
There are many types of vasculitis.
Each type involves inflamed blood vessels.
Most types differ in whom they have an effect on and the organs that are involved.
The most frequent type (polymyalgia rheumatica (PMR)) had an estimated cumulative prevalence (the number of people who had ever had the disease over a given period of time) of 2.27%.
The matching figure for the next most frequent (giant cell arteritis (GCA)) was 0.41%
Mostly Large Vessel Vasculitis
These types of vasculitis normally, but not always, affect the body’s larger blood vessels.
Behcet's Disease
Giant Cell Arteritis
Polymyalgia Rheumatica
Takayasu's Arteritis
Cogan's SyndromeMostly Medium Vessel Vasculitis
These forms of vasculitis normally but not always involve the body’s medium-sized blood vessels.
Buerger's Disease
Kawasaki Disease
Polyarteritis Nodosa
Central Nervous System VasculitisMostly Small Vessel Vasculitis
These forms of vasculitis normally but not always involve the body’s small blood vessels.
Churg-Strauss Syndrome
Henoch-Schonlein Purpura
Essential Mixed Cryoglobulinemia
Hypersensitivity Vasculitis
Microscopic Polyangiitis
Wegener's Granulomatosis
Diagnosis:
Angiography and biopsy of an involved organ are the best ways
Treatment:
Frequent prescription medicines utilized to treat vasculitis are:
1.Corticosteroids and
2.Cytotoxic medicines
3.Biologic medicines
TABLE OF CONTENT
Introduction
Chapter 1 Vasculitis Diseases
Chapter 2 Takayasu Arteritis
Chapter 3 Giant Cell Arteritis
Chapter 4 Polyarteritis Nodosa
Chapter 5 Polymyalgia Rheumatica
Chapter 6 Buerger’s Disease
Chapter 7 Kawasaki Disease
Chapter 8 Henoch Schonlein Purpura
Epilogue
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