The new, 2nd Edition of this practical guide employs a sign-oriented approach to the diagnosis of both common and rare medical disorders. This comprehensive collection of clinical pictures, organized by anatomical region, reflects actual clinical practice where a diagnosis has to be constructed from a single sign or a collection of signs. Fundamental, pathognomonic, and commonly seen specific and non-specific clinical signs are presented with clinical features highlighted for rapid recognition and interpretation. In addition, the book provides guidance on appropriate bedside clinical tests for establishing diagnoses.