The growth of uro-oncology has been one of the dramatic features of the past decade in urology. Basic science research into the immunol ogy and molecular biology of cancer is beginning to impact on clinical urology and this poses a number of problems, both for practising urologists and basic scientists. If they are going to contribute to future research in this area they will have to communicate with each other: at present there is a gap which is widening at an increasingly rapid rate. One of the aims of this book is to bridge this gap by collating the views of a group of internationally distinguished scientists and clinicians in order to make this information more easily accessible. It is intended that the book will be useful to any urologist interested in recent developments in uro-oncology both at the clinical and basic science level. I believe the book has a useful function not otherwise fulfilled by present texts. The first section of the book is directed towards bladder cancer.