In 1892, Andrew Taylor Still did the unimaginable when he accepted women and men equally in his newly opened American School of Osteopathy. Thomas Quinn, DO, showcases some of the valiant women who rose above adversity to become osteopathic doctors in those early years, and includes prominent female osteopathic physicians up to the present time. The stories of their fight against the inequality of the sexes in medicine are intertwined with the struggles of osteopathy to be accepted as a valid scientific practice, illuminating the innovative and determined individuals who helped osteopathic medicine develop into the flourishing profession it is today.