This proceedings volume, for the symposium in honor of Edward Teller's 100th anniversary, focuses on Teller's scientific legacy. This legacy includes some of the most fundamental insights into the quantum behaviors of molecules, nuclei, surfaces, solid state and spin systems and plasmas. Many of these are “brand names” from the canon of 20th-century physics and chemistry, such as Gamow–Teller transitions, the Jahn–Teller effect, Goldhaber–Teller resonances, the Lyddane–Sachs–Teller relation, the Brunauer–Emmett–Teller equation of state, and the MR2T2 algorithm. All of these have had a profound and continuing impact on science — as has Teller's work on level crossing, diamagnetism, and plasma and statistical physics. The legacies of these discoveries are discussed in this volume, as is Teller's role in applied science and education.