Tackling Exascale Software Challenges in Molecular Dynamics Simulations with GROMACS.- Weighted Decomposition in High-Performance Lattice-Boltzmann Simulations: Are Some Lattice Sites More Equal than Others.- Performance Analysis of a Reduced Data Movement Algorithm for Neutron Cross Section Data in Monte Carlo Simulations.- Nek5000 with OpenACC.- Auto-tuning an OpenACC Accelerated Version of Nek5000.- Development Environment for Exascale Applications Towards Exascale Co-Design in a Runtime System.- Overcoming Asynchrony: An Analysis of the Effects of Asynchronous Noise on Nearest Neighbor Synchronizations.- Memory Usage Optimizations for Online Event Analysis.- Towards Detailed Exascale Application Analysis - Selective Monitoring and Visualisation.- Performance Analysis of Irregular Collective Communication with the Crystal Router Algorithm.- The Architecture of Vistle, a Scalable Distributed Visualization System.