Antibody-Drug Conjugates and Cellular Metabolic Dynamics

Antibody-Drug Conjugates and Cellular Metabolic Dynamics

by Shuqing Chen and Jinbiao Zhan
Epub (Kobo), Epub (Adobe)
Publication Date: 19/04/2023

Share This eBook:

  $224.99

This book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs. This book combines the basic theory with the research technology. It canbe used as a reference book for students, teachers and researchers of biomedical field.

ISBN:
9789811956386
9789811956386
Category:
Biology
Format:
Epub (Kobo), Epub (Adobe)
Publication Date:
19-04-2023
Language:
English
Publisher:
Springer Nature Singapore

This item is delivered digitally

Reviews

Be the first to review Antibody-Drug Conjugates and Cellular Metabolic Dynamics.